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Osteoarthritis

Osteoarthritis

(OARSI 2014) A 600-patient randomized trial has found a glucosamine-chondroitin formulation non-inferior to celecoxib for the pain of knee osteoarthritis. Also, unlike placebo, it shows noteworthy effects on pain regions in the brain.

(OARSI 2014) More reasons to stay slim: A small prospective study finds that people with moderate hip osteoarthritis who have hip replacement within a decade are larger and have less normal gait.

An observational study finds that regularly drinking low-fat milk slows joint narrowing in arthritic knees. Needs confirmation, but the prospective remedy is harmless and promising.

The best news for rheumatologists from last year, in this review, involved osteoarthritis, psoriatic arthritis, and rheumatoid arthritis -- including a good way to assess cardiovascular risk in RA.

In a small placebo-controlled trial, methotrexate significantly improved pain and other symptoms of knee osteoarthritis and predictably modest adverse effects.

ACR and EULAR are soliciting proposals for collaborative projects to update classification and response criteria for a number of high-priority rheumatologic conditions.

(AAOS 2014) A prospective registry study in the UK shows that for patients with all but the most severe knee OA, the most important gains from knee replacement surgery will be in pain rather than in physical function.

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