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Osteoarthritis

Osteoarthritis

(ACR2014) A test for 14-3-3-eta, a joint-derived protein that contributes to erosion, proves a powerful aid to diagnosis of rheumatoid arthritis and ankylosing spondylitis, and may also predict response to treatment.

"Paleoradiology" has now disputed claims that ankylosing spondylitis plagued some royal Egyptians in antiquity. This is the latest of several revelations about the provenance of some rheumatic conditions, based on imaging of ancient remains.

Here Dr. DeMarco shows how to guide an injection of the hip using ultrasound. The trick is training yourself to identify the femoral neck and head and the trochanter, and then rotating the sensor to reveal the orientation of that particular joint, beneath all that tissue.

More careful patient selection is making knee replacement ever safer, judging from data in a huge British registry. But the analysis may generate an unfair bias favoring total over partial replacement.

Pfizer expects to release Embeda (morphine sulfate and naltrexone hydrochloride), approved in 2009 based on osteoarthritis studies but withdrawn by another firm in 2011 due to concerns over abuse, sometime early next year.

Neither needle nor laser acupuncture demonstrate a clinical benefit over placebo in older patients with moderate or severe chronic knee pain.

Overlaps between PsA and OA can produce diagnostic confusion. Multimodality imaging may help sort things out

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