Linagliptin achieves significant improvements in glycemic control in a pooled analysis of clinical trials. And a separate randomized trial shows that it can spare insulin and protect kidneys in patients with type 2 diabetes and severe renal insufficiency.
New alternatives to docetaxel (including cabozanitib and abiraterone) are hot on its heels for treatment of prostate cancer, and another drug has potential to address docetaxel resistance.
An hour of continuous EEG monitoring can identify seiaures among patients with spells and altered mental status. Spells just before EEG spell out a worse prognosis.
Evidence suggests that temozolomide-based treatments for glioma tend to induce secondary blood cancers. Also, why FDG-PET may be preferable to MRI for planning interventions.
New research clarifies the relationship between psychosis and violence, and suggests that depression may be more closely linked than psychosis to repeated violence.
New analyses offer lists of factors that may influence survival after surgery for nonsmall-cell lung cancer and others that take into account the redefinition of TNM classifications
New guidelines for mantle cell lymphoma have been released by the European Society for Medical Oncology, and details of a study that offers a new regimen for some patients with the malignancy.
The one single measure that adequately captures the full burden of depression, according to data from the STAR*D study, is the Individual Burden of Illness Index for Depression, which incorporates multidimensional patient-reported outcomes prior to and following treatment.
In children, bilateral otitis media appears to be only slightly more severe than unilateral, according to a study whose authors offer advice on how to judge severity. And a systematic review offers guidance on when to use antibiotics.
