FEATURED SEARCH: precipitating factors appendicitis
Fusobacteria were a characteristic component of mucosal lesions in 62% of patients with proven appendicitis, in a comparative study by scientists and doctors from Germany. The presence of these bacteria correlated with the severity of the appendicitis, and they were completely absent in cecal biopsies from diseased or healthy controls. Other bacterial species also found in mucosal lesions from appendicitis patients were not associated with the severity of the disease.
RESULT: Acute appendicitis is characterised by local invasion with Fusobacterium nucleatum/necrophorum
Gut | Jan 1, 2011 (Free abstract. Full text: $30)
Scientists in Korea found in a retrospective study that C-reactive protein (CRP) correlated with the severity of acute appendicitis and that white blood cell counts may be a useful marker for early acute appendicitis. This is interesting in light of the previous study, given that CRP is a marker of inflammation that binds to cell-surface proteins on dead and dying cells and on bacteria.
RESULT: Acute appendicitis: relationships between CT-determined severities and serum white blood cell counts and C-reactive protein levels
British Journal of Radiology | Dec 1, 2010 (Free abstract. Full text: $15)
Based on a systematic review, UCLA pediatric surgeons offer guidance on the antibiotic treatment of children with appendicitis. They suggest preferential use of broad-spectrum antibiotics.
RESULT: Antibiotics and appendicitis in the pediatric population: an American Pediatric Surgical Association Outcomes and Clinical Trials Committee Systematic Review
Journal of Pediatric Surgery | Nov 1, 2010 (Free abstract. Full text: $31.50)