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Is lenalidomide effective against multiple myeloma as more than just a second-line agent?

For which adolescent who "cuts" does self-harm mean suicide ? A battery of tests predicts who's at serious risk. For one bizarre subtype of body integrity identity disorder, the cuts go very deep.

In aggressive B-cell lymphoma, attention to the qualities of subtypes and microenvironmental factors may pay off in therapy.

In primary care, low back pain can be treated cost-effectively with screening and targeting treatment by subgroups.

We know that anti-resorptive medications are effective at minimizing bone loss. But we are also discovering adverse effects in a few patients. With the increasing average lifespan, whether and when to stop has become an interesting question.

Many ulcerative colitis patients who have surgery could be helped by probiotics. But they may not help other UC patients very much.

It may not prevent transition to psychosis, but studies show that CBT can reduce its severity and help patients deal with emotional issues.

New studies examine the cost-benefit equation for proton beam therapy, whose utilization appears to be governed more at present by availability than by efficacy.

A retrospective study suggests that HbA1c plus FPG should prove useful in assessing diabetes risk in healthy patients.

A case report about managing a very rare form, and guidelines for managing the second-most common type.

Systematic reviews raise issues about the long-term benefits of early treatment for asymptomatic patients with multiple myeloma, and about the best way to treat bone pain in breast cancer.

At least at VA hospitals, obesity is one rare physical condition for which psychiatric patients seem to get better care than people with purely medical conditions. The effect of medications is only one of many reasons why extra vigilance for medical problems is important for people who have serious mental health issues.

There's an urgent need to evaluate surgeries for trigeminal neuralgia, says the Cochrane Collaboration. A new imaging method could help.

Salvage radiotherapy provides long-term protection against biochemical failure, in a new study from Spain.

Women with chronic kidney disease no longer need to avoid pregnancy, according to the experts. But their situation is so new that it's difficult to give them informed counseling.