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HPV

 

TheBasics

•  Most prevalent sexually transmitted infection in the United States

•  Present in the genital tract of many sexually active individuals

•  Transmitted by direct contact with skin or mucosal surfaces

•  Responsible for genital warts (condyloma acuminata), usually benign

•  Causes about 70% of cervical cancers

•  Increasingly associated with squamous cell carcinoma of the head and neck

•  Occurs in 15 cancer-causing strains; HPV16 and HPV18 are most virulent

•  Vaccines are highly effective in preventing genital intraepithelial neoplasia (cervical and anal)

•  Two vaccines are approved:

                Cervarix (bivalent HPV 16/18) against cervical cancer
                Gardasil (quadrivalent HVP 16/18/6/11) against cervical or anal cancer

 

GUIDELINES

 

Prevention of Human Papillomavirus Infection: Provisional Recommendations for Immunization of Girls and Women with Quadrivalent Human Papillomavirus Vaccine
American Academy of Pediatrics

 

Quadrivalent Human Papillomavirus Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP)

 

American Cancer Society Guideline for Human Papillomavirus (HPV) Vaccine Use to Prevent Cervical Cancer and Its Precursors

 

RESOURCES
 

EMedicine:  Human Papillomavirus

 

FDA Licensure of Bivalent Human Papillomavirus Vaccine (HPV2, Cervarix) for use in Females and Updated HPV Vaccination Recommendations from the Advisory Committee on Immunization Practices (ACIP)
CDC Morbidity and Mortality Weekly Reports, May 2010

 

Efficacy and Safety of Prophylactic Vaccines against Cervical  HPV Infection and Diseases among Women:  A Systematic Review & Meta-Analysis
BMC Infectious Diseases, January 2011


Efficacy of Quadrivalent HPV Vaccine against HPV Infection and Disease in Males
New England Journal of Medicine, February 2011

 

Oropharyngeal Cancer Epidemic and Human Papillomavirus
CDC Emerging Infectious Diseases, November 2010


Variables Associated With Human Papillomavirus (HPV) Acceptance by Men
Journal of the American Board of Family Medicine, January 2009

 

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ClinicalTrials

High prevalence and incidence of human papillomavirus in a cohort of healthy young African female subjects.
researchonline.lshtm.ac.uk -
Economic analyses to support decisions about HPV vaccination in low- and middle-income countries: a consensus report and guide for analysts.
researchonline.lshtm.ac.uk -
Transmission of carcinogenic human papillomavirus types from mother to child: a meta-analysis of published studies
journals.lww.com - 4/30/13
More Results

FeaturedArticles

October 24, 2012
Oral HSV and HPV Disease: A Photo Essay
More than 100 types of HPV inhabit the oral region. The HPV-16 type is highly associated with oral squamous cell carcinoma. More »
July 25, 2012
HPV Infections Last for More Than 2 Years
Reason for continued vigilance about human papillomavirus infection: The virus persists, and the vaccine covers only about half of infected women, a study shows. More »
January 17, 2012
HPV in Head and Neck Cancers: A Useful Bystander?
It's easy to jump to the conclusion that human papillomavirus is behind the rise in head and neck cancers. But a UK study suggests otherwise. More »
January 6, 2012
Radiology Quiz: Bronchiolitis? Pneumonia? Croup? Epiglottitis?
Hoarseness developed in a 27-month-old girl who was previously treated in the ED for a presumed asthma exacerbation and bronchiolitis. More »
November 9, 2011
Podcast: Addressing Parents’ Concerns About Vaccinating Boys Against HPV Infection
You and your colleagues are undoubtedly hearing questions from a lot of concerned parents about the new... More »
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PubMed

Awareness, acceptability and uptake of human papilloma virus vaccine among Cameroonian school-attending female adolescents.
pubmed.gov - 11/30/12
Knowledge, attitudes, practice on human papilloma virus and cervical cancer among Trinidadian women.
pubmed.gov - 9/30/12
HPV: diagnosis, prevention, and treatment.
pubmed.gov - 8/31/12
Association between the evidence of human papilloma virus infection in bladder transitional cell carcinoma in men and cervical dysplasia in their spouses.
pubmed.gov - 8/31/12
Photodynamic therapy of cervical intraepithelial neoplasia 1-3 and human papilloma virus (HMV) infection with methylaminolevulinate and hexaminolevulinate--a double-blind, dose-finding study.
pubmed.gov - 7/31/12
More Results


TopicIndex

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Brenda Edwards, CPC,  May 15, 2013
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Cheyenne Brinson,  May 15, 2013
Failing to adopt widely available billing and collections technology can cost medical practices big. Here's how to do it right.
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It’s becoming increasingly difficult for private medical practices to thrive. Here’s what’s driving the trend toward consolidation.
 

 

PatientResources

Human Papillomavirus Infection
American College of Obstetricians and Gynecologists

 

Human Papillomavirus Vaccine
American College of Obstetricians and Gynecologists

 

Human Papillomavirus
Centers for Disease Control and Prevention

 

Human Papillomavirus (HPV)
familydoctor.org (American Academy of Family Physicians)

 

HPV
Medline Plus (National Institutes of Health)

 

 

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