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HPV

 

TheBasics

•  Most prevalent sexually transmitted infection in the United States

•  Present in the genital tract of many sexually active individuals

•  Transmitted by direct contact with skin or mucosal surfaces

•  Responsible for genital warts (condyloma acuminata), usually benign

•  Causes about 70% of cervical cancers

•  Increasingly associated with squamous cell carcinoma of the head and neck

•  Occurs in 15 cancer-causing strains; HPV16 and HPV18 are most virulent

•  Vaccines are highly effective in preventing genital intraepithelial neoplasia (cervical and anal)

•  Two vaccines are approved:

                Cervarix (bivalent HPV 16/18) against cervical cancer
                Gardasil (quadrivalent HVP 16/18/6/11) against cervical or anal cancer

 

GUIDELINES

 

Prevention of Human Papillomavirus Infection: Provisional Recommendations for Immunization of Girls and Women with Quadrivalent Human Papillomavirus Vaccine
American Academy of Pediatrics

 

Quadrivalent Human Papillomavirus Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP)

 

American Cancer Society Guideline for Human Papillomavirus (HPV) Vaccine Use to Prevent Cervical Cancer and Its Precursors

 

RESOURCES
 

EMedicine:  Human Papillomavirus

 

FDA Licensure of Bivalent Human Papillomavirus Vaccine (HPV2, Cervarix) for use in Females and Updated HPV Vaccination Recommendations from the Advisory Committee on Immunization Practices (ACIP)
CDC Morbidity and Mortality Weekly Reports, May 2010

 

Efficacy and Safety of Prophylactic Vaccines against Cervical  HPV Infection and Diseases among Women:  A Systematic Review & Meta-Analysis
BMC Infectious Diseases, January 2011


Efficacy of Quadrivalent HPV Vaccine against HPV Infection and Disease in Males
New England Journal of Medicine, February 2011

 

Oropharyngeal Cancer Epidemic and Human Papillomavirus
CDC Emerging Infectious Diseases, November 2010


Variables Associated With Human Papillomavirus (HPV) Acceptance by Men
Journal of the American Board of Family Medicine, January 2009

 

TipsandTools


ClinicalTrials

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FeaturedArticles

Oral Cancer: From First Detection to Disease Spread
Why the USPSTF has declined to recommend regular screening for oral cancer in primary care, and a new biomarker for metastasis in oral squamous cell carcinoma. More »
HPV Vaccination: Impact of Culture and Language on Initiation, Completion
English- and Spanish-speaking parents cited widely differing reasons for avoiding vaccination for their eligible daughters or failing to ensure the 3 doses were received. More »
Primary Care Physicians Play Key Role in Promoting HPV Vaccine to Boys' Parents
Most parents of boys aged 9 to 18 years do not know that an HPV vaccine is available for their sons. One major factor is a lack of information. This is where you play a vital role. More »
Oral HSV and HPV Disease: A Photo Essay
More than 100 types of HPV inhabit the oral region. The HPV-16 type is highly associated with oral squamous cell carcinoma. More »
HPV Infections Last for More Than 2 Years
Reason for continued vigilance about human papillomavirus infection: The virus persists, and the vaccine covers only about half of infected women, a study shows. More »
Showing 1 - 5 of 58 results.
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PubMed

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PatientResources

Human Papillomavirus Infection
American College of Obstetricians and Gynecologists

 

Human Papillomavirus Vaccine
American College of Obstetricians and Gynecologists

 

Human Papillomavirus
Centers for Disease Control and Prevention

 

Human Papillomavirus (HPV)
familydoctor.org (American Academy of Family Physicians)

 

HPV
Medline Plus (National Institutes of Health)

 

 

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