A statistically significant association exists between efavirenz for initial HIV therapy and the risk suicidality. When this drug is given as a component of an antiretroviral drug regimen, patients should be monitored carefully for the possibility of deterioration of their depression or evidence of suicidal behavior.
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Women of all races and ethnicities are less likely to take antiretroviral therapy than men. Consideration of both gender and race/ethnicity is thus needed to identify areas for targeted intervention to improve outcomes relevant to specific groups of women."