Major depressive disorder (MDD): Interferes with daily activities. May recur several times Dysthymia: Non-disabling. Chronic symptoms may alternate with MDD Bipolar disorder: Mood cycles between highs (mania) and lows (depression)
Selective serotonin reuptake inhibitors have been shown effective in the treatment of depression with psychosis. This efficacy appears to correlate with the SSRIs’ level of affinity at the sigma-1 receptors in the brain. What role does the sigma-1 receptor play in psychotic depression? Based on this... More »
There is growing epidemiologic and clinical data that confirm progressive hypothalamic-pituitary-gonadal hypofunctioning in aging men. What role does the HPG axis play in the complex psychobiology of male sexual and affective disorders? The treatment rationale, clinical indications and risks in... More »
When a family member is diagnosed with depression the whole family is affected. Additional family and marital stresses imposed on the patient with depression can add to the severity of depression and affect long-term remission rates. In order to ensure the best possible success in treatment, the... More »
Health-related quality of life can provide a simultaneous and net assessment of the therapeutic and adverse affects of psychiatric treatments for depression. While the cognitive side effects of ECT might be thought of as a limiting factor in HRQOL gains, they have not been systematically studied... More »
By 2020, depression will be the second leading cause of death and disability worldwide. As the importance of depression as a public health problem has been reinforced, research efforts have followed different paths. Read about some of the latest developments. More »
Psychopaths share characteristics with serial killers and successful professions, such as surgeons, high-powered executives, and politicians, according to a review of a new book that explores several scientific approaches to identifying aspects of psychopathic traits.
Three easy-to-obtain pieces of information followed by a systematic recording of a general practitioners' prognostic judgment provide a simple, generic assessment of older patients presenting with musculoskeletal problems.
Five Steps to Improving Patient Access Judy Capko, May 21, 2013 Patient access is getting increased attention through reform initiatives. Here are five steps you can take to make sure patients get appropriate access to care in your office.