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Calibrating Interstitial Brachytherapy in Cervical Cancer

Calibrating Interstitial Brachytherapy in Cervical Cancer

Whole-pelvis intensity modulated radiotherapy has become a standard of care in cervical cancer, but efforts to find better and more specific ways to deliver interstitial brachytherapy are ongoing. Unfortunately, a simultaneous integrated boost (SIB) – with the aim of sending an accelerated radiation dose to gross disease – may not be option, according to Swiss radiation oncologists. They explain why SIB carries a twofold risk of underdosing the tumor while overdosing adjacent structures.

RESULT: Retrospective feasibility study of simultaneous integrated boost in cervical cancer using tomotherapy: the impact of organ motion and tumor regression
Radiation Oncology | Jan 03, 2013 (FREE FULL TEXT)


Preplanning for multifractionated pelvic brachytherapy needs to account for interfraction needle displacements, urged clinicians from India. They looked at 3-D needle displacements during multifractionated interstitial brachytherapy for cervical cancers, focusing on the cranial, caudal, anterior, posterior, right, and left directions. In a prospective study, they break down which one of those areas saw clinically significant needle displacement.

RESULT: Quality assurance of multifractionated pelvic interstitial brachytherapy for postoperative recurrences of cervical cancers: a prospective study
International Journal of Radiation Oncology, Biology, Physics (PubMed) | Mar 12, 2012 (Free abstract. Full text $30)


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