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Newer Drugs Used to Initiate Treatment for Bipolar Disorder

Newer Drugs Used to Initiate Treatment for Bipolar Disorder

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The introduction of new drugs for bipolar disorder has greatly expanded the armamentarium available for treatment. These authors conducted a study to examine utilization and patterns of psychopharmacologic treatment during a 1-year follow-up period among patients with newly diagnosed bipolar disorder from 2001 to 2010.

A total of 2703 patients with newly diagnosed bipolar disorder from 2001 to 2010 were identified from the National Health Insurance Research Database in Taiwan. The authors assessed prescription records related to 4 kinds of psychopharmacologic medication, including antipsychotics, antidepressants, mood stabilizers, and benzodiazepines, as well as health-care utilization in a 1-year follow-up period. They noted that the ratio of good adherence was relatively low during the study period.

They found that the use of first-generation antipsychotics, selective serotonin reuptake inhibitors, tricyclic antidepressants, lithium, carbamazepine, and benzodiazepines had declined. On the other hand, the use of second-generation antipsychotics, serotonin and norepinephrine reuptake inhibitors, lamotrigine, and valproate had increased markedly.

The authors noted the importance of further investigations into the causes and outcomes for polytherapy and nonadherence to psychotropic medications among bipolar disorder patients.

Result: Utilization of psychopharmacological treatment among patients with newly diagnosed bipolar disorder from 2001 to 2010. Journal of Clinical Psychopharmacology | Feb 1, 2016 (Free abstract. Full text $53.35)  

 

 

 
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