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Genetic Variants Modulate Glutamate in Bipolar Disorder and Schizophrenia
New research is clarifying the link between brain glutamate levels and risk for psychosis in bipolar, as well as genes associated with the glutamate pathway that are overexpressed in bipolar.
Dopamine Signaling Linked to Reward Processing in Bipolar Disorder
Deficits in dopamine signaling are linked strongly to poor decision making in patients with bipolar. Is it time to stratify treatment based on this understanding?
Naltrexone Does Not Stabilize Bipolar in Absence of Alcohol Abuse
Three studies investigate patterns of substance abuse among patients with bipolar disorder, and agents that may help.
Managing Late-Life Bipolar Disorder: Current Issues and Clinical Tips
Key issues about geriatric bipolar disorder—epidemiology, assessment, medical and psychiatric comorbidity, and treatment—are the focus.
Art Therapy in a Patient With Bipolar Disorder: Pictures Speak More Than a Thousand Words
Here: the case of a woman with bipolar disorder who was admitted for aggressive behavior and nonadherence to medications. Art therapy and pharmacotherapy played a pivotal role in her recovery.
Mini-quiz: Strategies for Switching Antipsychotics
When acute, severe adverse effects from a pre-switch antipsychotic occurs, what strategy is recommended? Take the quiz and learn more.
Early Lithium Treatment Boosts Response in Bipolar Disorder
Treating bipolar with lithium at its earliest onset increases the odds of success. However, vigilance for toxicities is in order, as two recent case studies demonstrate.
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