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Cannabis and Psychosis: What’s Behind the Link

Cannabis and Psychosis: What’s Behind the Link

FEATURED SEARCH TERM:   cannabis induced psychosis



Marijuana is known to induce acute psychotic symptoms, and its chronic use may increase the risk of schizophrenia. Functional MRIs show that the primary psychoactive ingredient in marijuana, Δ9-tetrahydrocannibinol (THC), can significantly increase the severity of psychotic symptoms compared with placebo and another ingredient, cannabidiol. The ingredients in marijuana appear to affect regions of the brain that contribute to salience, a fundamental factor underlying psychosis, state the authors of the report below.

RESULT: Induction of Psychosis by {Delta}9-Tetrahydrocannabinol Reflects Modulation of Prefrontal and Striatal Function During Attentional Salience Processing
Archives of General Psychiatry | Jan 1, 2012 (Free abstract. Full text $30)



Strong evidence supports cannabis consumption as a risk factor for the development of psychotic symptoms and schizophrenia, say the authors of this review. They contend that cannabis use worsens the clinical course and overall prognosis of schizophrenia, and strongly suggest that clinicians assess patients for cannabis use and educate them about the drug’s potential dangers as well as the benefits of quitting.


RESULT: The Cannabis-Psychosis Link
PsychiatricTimes | Jan 12, 2012 (FREE FULL TEXT)


 

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