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What accounts for the legendary creativity of patients with bipolar disorder? Long assumed to be an effect of the manic phase, it may have as much to do with heightened sensory capacities, according to a new report.

Both emotional assessments using mood scales and functional MRI are helping to define the ways in which mood regulation and perception are disturbed in the affective states of bipolar disorder.

Genome-wide studies implicate distinctive signaling pathways in bipolar, and functional MRI points to elements of reward-seeking behavior as common to patients with the disorder.

Several recent studies show an association between influenza during pregnancy and risk of bipolar -- particularly bipolar psychosis.

Evidence differs on whether memantine is a useful adjunct to bipolar treatment. But it does suggest interesting immune phenomena underlying the condition.

For bipolar patients on long-term lithium treatment, vigilance for cardiac adverse effects is warranted.

New research suggests ways to optimize the efficacy of BRAF and MEK inhibitors in melanoma.

Bereavement and other stress in early life, including the perinatal period, appears to increase the risk for bipolar. Pregnancy may also be a risk factor for the mother.

Lack of family support and persistent substance abuse are risk factors for disengaging from the earliest stages of treatment for new-onset psychosis.

A theoretical dispute over whether risk for Guillain-Barre syndrome is increased within the first few weeks after a flu shot. An expert agrees that risk for the syndrome is even greater after actually catching the flu.


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