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RT Offers Hope for Prostate Cancer Patients With Adverse PSA Levels

May 7, 2012

FEATURED SEARCH TERM: PSA after surgery

Biochemical control after radical prostatectomy in high-risk prostate cancer patients has proven disappointing, even when paired with low-dose external-beam radiation therapy (EBRT). However, high radiation doses have demonstrated improved biochemical and clinical results. Radiation oncologists in Spain adopted the combination of EBRT and high-dose-rate (HDR) intensity modulated brachytherapy as their standard treatment protocol for patients with prostate-specific antigen (PSA) levels of more than >20 ng/ml. In a long-term outcomes report, they outline the advantages that EBRT with an HDR boost offered over conventional surgery, including a longer time to PSA failure.

RESULT: Long-term biochemical results after high-dose-rate intensity modulated brachytherapy with external beam radiotherapy for high risk prostate cancer
Radiation Oncology | Mar 7, 2012 (FREE FULL TEXT)

Despite supportive data for adjuvant radiation therapy after radical prostatectomy for high-risk prostate cancer, many clinicians are still cautious about salvage radiotherapy. A recent survey queried radiation oncology and urologists on when and why they recommend radiation therapy after radical prostatectomy. Not surprisingly, their responses differed by their specialty, their understanding of radiotherapy, and their concerns about treatment-related toxicity.

RESULT: Physician beliefs and practices for adjuvant and salvage radiation therapy after prostatectomy
International Journal of Radiation Oncology, Biology, Physics (PubMed) | Feb 1, 2012 (Free abstract. Full text $31.50)

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