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Does good insight at start of pharmacologic treatment enhance outcomes?

Newer classes of drugs are being chosen over traditional agents as treatment for patients newly diagnosed with bipolar disorder.

Limbic brain areas in bipolar disorder patients showed BMI-related volume reductions, even in early-stage disease.

This study found a higher number of past manic episodes had the strongest correlation with the poorest outcomes in verbal memory testing.

Lithium therapy in bipolar disorder is associated with chronic kidney disease but not with an increased rate of end-stage disease.

What would lead clinicians to prescribe a novel antipsychotic as first-line therapy for manic symptoms over standard bipolar agents like lithium and valproate?

Depressive symptoms improved in bipolar patients given instruction on the role of circadian rhythm disturbance in mental disorders.

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